Tasting Phenylthiocarbamide (PTC): A New Integrative Genetics Lab with an Old Flavor
نویسندگان
چکیده
منابع مشابه
Phenylthiocarbamide tasting in a sample of twins.
1. Twenty-eight pairs of monozygotic and eighteen pairs of dizygotic twins were tested for their ability to taste phenylthiocarbamide (P.T.C.) by the method of Harris & Kalmus (1949). 2. Much greater variance in threshold levels was detected within the DZ than within the MZ pairs and this confirms the genetic origin of most variation in ability to taste this substance. 3. Variance in threshold ...
متن کاملThe genetics of phenylthiocarbamide perception.
The ability to taste the bitter compound phenylthiocarbamide (PTC) and related chemicals is bimodal, and all human populations tested to date contain some people who can and some people who cannot taste PTC. Why this trait has been maintained in the population is uncertain but this polymorphism may influence food selection, nutritional status or thyroid metabolism. The gene product that gives r...
متن کاملPhenylthiocarbamide: a 75-year adventure in genetics and natural selection.
VARIATION in taste sensitivity to the bitter compound phenylthiocarbamide (PTC) is one of the best known Mendelian traits in human populations, ranking alongside eye color and blood types in the canon of classic examples. Much of PTC’s appeal arises from the fact that it is nearly impossible to guess one’s phenotype until explicitly tested, yet, when tested, the phenotype is so striking as to b...
متن کاملPhenylthiocarbamide tasting and family history of depression, revisited: low rates of depression in families of supertasters.
Past studies suggest that phenylthiocarbamide (PTC) taste status is related to vulnerability to depression, such that those sensitive to PTC are more vulnerable. We questioned this, reasoning that those insensitive to PTC may be more vulnerable (because they may have lower hedonic tone and higher risk for alcohol abuse). Forty-two volunteers responded to questionnaires regarding family history ...
متن کاملAssociations of phenylthiocarbamide tasting to alcohol problems and family history of alcoholism differ by gender.
Past research associating phenylthiocarbamide/propylthiouracil (PTC/PROP) taste status with alcoholism has produced equivocal results. Some have found higher proportions of nontasters among those with a family history of alcoholism than controls, whereas others have not. The purpose of this study was to investigate the relationship between PTC taste status, alcohol problems, and family history ...
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ژورنال
عنوان ژورنال: The American Biology Teacher
سال: 2008
ISSN: 0002-7685,1938-4211
DOI: 10.1662/0002-7685(2008)70[23:tppani]2.0.co;2